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Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory
Recent evidence has placed the unfolded protein response (UPR) at the centre of pathological processes leading to neurodegenerative disease. The translational repression caused by UPR activation starves neurons of the essential proteins they need to function and survive. Restoration of protein synth...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053297/ https://www.ncbi.nlm.nih.gov/pubmed/25556298 http://dx.doi.org/10.1111/nan.12211 |