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Cerebrospinal fluid total tau concentration predicts clinical phenotype in Huntington's disease

Huntington's disease (HD) is a hereditary neurodegenerative condition with no therapeutic intervention known to alter disease progression, but several trials are ongoing and biomarkers of disease progression are needed. Tau is an axonal protein, often altered in neurodegeneration, and recent st...

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Detalles Bibliográficos
Autores principales: Rodrigues, Filipe Brogueira, Byrne, Lauren, McColgan, Peter, Robertson, Nicola, Tabrizi, Sarah J., Leavitt, Blair R., Zetterberg, Henrik, Wild, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053298/
https://www.ncbi.nlm.nih.gov/pubmed/27344050
http://dx.doi.org/10.1111/jnc.13719