Druggability analysis and classification of protein tyrosine phosphatase active sites

Protein tyrosine phosphatases (PTP) play important roles in the pathogenesis of many diseases. The fact that no PTP inhibitors have reached the market so far has raised many questions about their druggability. In this study, the active sites of 17 PTPs were characterized and assessed for its ability...

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Detalles Bibliográficos
Autores principales: Ghattas, Mohammad A, Raslan, Noor, Sadeq, Asil, Al Sorkhy, Mohammad, Atatreh, Noor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053377/
https://www.ncbi.nlm.nih.gov/pubmed/27757011
http://dx.doi.org/10.2147/DDDT.S111443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053377/
https://www.ncbi.nlm.nih.gov/pubmed/27757011
http://dx.doi.org/10.2147/DDDT.S111443

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