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Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans
Low rates of homologous integration have hindered molecular genetic studies in Cryptococcus neoformans over the past 20 years, and new tools that facilitate genome manipulation in this important pathogen are greatly needed. To this end, we have investigated the use of a Class 2 CRISPR system in C. n...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053423/ https://www.ncbi.nlm.nih.gov/pubmed/27711143 http://dx.doi.org/10.1371/journal.pone.0164322 |