Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans

Low rates of homologous integration have hindered molecular genetic studies in Cryptococcus neoformans over the past 20 years, and new tools that facilitate genome manipulation in this important pathogen are greatly needed. To this end, we have investigated the use of a Class 2 CRISPR system in C. n...

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Detalles Bibliográficos
Autores principales: Arras, Samantha D. M., Chua, Sheena M. H., Wizrah, Maha S. I., Faint, Joshua A., Yap, Amy S., Fraser, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053423/
https://www.ncbi.nlm.nih.gov/pubmed/27711143
http://dx.doi.org/10.1371/journal.pone.0164322

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