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The Effect of Gender on Mesenchymal Stem Cell (MSC) Efficacy in Neonatal Hyperoxia-Induced Lung Injury

BACKGROUND: Mesenchymal stem cells (MSC) improve alveolar and vascular structures in experimental models of bronchopulmonary dysplasia (BPD). Female MSC secrete more anti-inflammatory and pro-angiogenic factors as compared to male MSC. Whether the therapeutic efficacy of MSC in attenuating lung inju...

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Detalles Bibliográficos
Autores principales: Sammour, Ibrahim, Somashekar, Santhosh, Huang, Jian, Batlahally, Sunil, Breton, Matthew, Valasaki, Krystalenia, Khan, Aisha, Wu, Shu, Young, Karen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053475/
https://www.ncbi.nlm.nih.gov/pubmed/27711256
http://dx.doi.org/10.1371/journal.pone.0164269