Stoichiometric Representation of Gene–Protein–Reaction Associations Leverages Constraint-Based Analysis from Reaction to Gene-Level Phenotype Prediction

Genome-scale metabolic reconstructions are currently available for hundreds of organisms. Constraint-based modeling enables the analysis of the phenotypic landscape of these organisms, predicting the response to genetic and environmental perturbations. However, since constraint-based models can only...

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Detalles Bibliográficos
Autores principales: Machado, Daniel, Herrgård, Markus J., Rocha, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053500/
https://www.ncbi.nlm.nih.gov/pubmed/27711110
http://dx.doi.org/10.1371/journal.pcbi.1005140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053500/
https://www.ncbi.nlm.nih.gov/pubmed/27711110
http://dx.doi.org/10.1371/journal.pcbi.1005140

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