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Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone

BACKGROUND: Benign human prostate tubule-initiating cells (TIC) and aggressive prostate cancer display common traits, including tolerance of low androgen levels, resistance to apoptosis, and microenvironment interactions that drive epithelial budding and outgrowth. TIC can be distinguished from epit...

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Detalles Bibliográficos
Autores principales: Liu, Sandy, Cadaneanu, Radu M., Zhang, Baohui, Huo, Lihong, Lai, Kevin, Li, Xinmin, Galet, Colette, Grogan, Tristan R., Elashoff, David, Freedland, Stephen J., Rettig, Matthew, Aronson, William J., Knudsen, Beatrice S., Lewis, Michael S., Garraway, Isla P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053503/
https://www.ncbi.nlm.nih.gov/pubmed/27711225
http://dx.doi.org/10.1371/journal.pone.0163232