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The Association between Elevated Levels of Peripheral Serotonin and Its Metabolite – 5-Hydroxyindoleacetic Acid and Bone Strength and Metabolism in Growing Rats with Mild Experimental Chronic Kidney Disease

Chronic kidney disease (CKD) is associated with disturbances in bone strength and metabolism. The alterations of the serotonergic system are also observed in CKD. We used the 5/6 nephrectomy model of CKD to assess the impact of peripheral serotonin and its metabolite– 5-hydroxyindoleacetic acid on b...

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Detalles Bibliográficos
Autores principales: Pawlak, Dariusz, Oksztulska-Kolanek, Ewa, Znorko, Beata, Domaniewski, Tomasz, Rogalska, Joanna, Roszczenko, Alicja, Brzóska, Małgorzata Michalina, Pryczynicz, Anna, Kemona, Andrzej, Pawlak, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053519/
https://www.ncbi.nlm.nih.gov/pubmed/27711209
http://dx.doi.org/10.1371/journal.pone.0163526