A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues

Heritable epigenetic changes underlie the ability of cells to differentiate into distinct cell types. Here, we demonstrate that the fungal pathogen Candida tropicalis exhibits multipotency, undergoing stochastic and reversible switching between three cellular states. The three cell states exhibit un...

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Detalles Bibliográficos
Autores principales: Anderson, Matthew Z., Porman, Allison M., Wang, Na, Mancera, Eugenio, Huang, Denis, Cuomo, Christina A., Bennett, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053522/
https://www.ncbi.nlm.nih.gov/pubmed/27711197
http://dx.doi.org/10.1371/journal.pgen.1006353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053522/
https://www.ncbi.nlm.nih.gov/pubmed/27711197
http://dx.doi.org/10.1371/journal.pgen.1006353

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