Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism

PURPOSE: We recently demonstrated that histone deacetylase (HDAC) inhibitors can “reprogram” differentiated triple-negative breast cancer cells to become quiescent stem-like cancer cells. We hypothesized that the metabolic state of such cells differs from that of their differentiated progeny. RESULT...

Descripción completa

Detalles Bibliográficos
Autores principales: Debeb, Bisrat G., Lacerda, Lara, Larson, Richard, Wolfe, Adam R., Krishnamurthy, Savitri, Reuben, James M., Ueno, Naoto T., Gilcrease, Michael, Woodward, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053589/
https://www.ncbi.nlm.nih.gov/pubmed/27078845
http://dx.doi.org/10.18632/oncotarget.8631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053589/
https://www.ncbi.nlm.nih.gov/pubmed/27078845
http://dx.doi.org/10.18632/oncotarget.8631

Ejemplares similares