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Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism

PURPOSE: We recently demonstrated that histone deacetylase (HDAC) inhibitors can “reprogram” differentiated triple-negative breast cancer cells to become quiescent stem-like cancer cells. We hypothesized that the metabolic state of such cells differs from that of their differentiated progeny. RESULT...

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Detalles Bibliográficos
Autores principales:	Debeb, Bisrat G., Lacerda, Lara, Larson, Richard, Wolfe, Adam R., Krishnamurthy, Savitri, Reuben, James M., Ueno, Naoto T., Gilcrease, Michael, Woodward, Wendy A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053589/ https://www.ncbi.nlm.nih.gov/pubmed/27078845 http://dx.doi.org/10.18632/oncotarget.8631

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