BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia

Oncogene inactivation in both clinical targeted therapies and conditional transgenic mouse cancer models can induce significant tumor regression associated with the robust induction of apoptosis. Here we report that in MYC-, RAS-, and BCR-ABL-induced acute lymphoblastic leukemia (ALL), apoptosis upo...

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Detalles Bibliográficos
Autores principales: Li, Yulin, Deutzmann, Anja, Choi, Peter S., Fan, Alice C., Felsher, Dean W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053622/
https://www.ncbi.nlm.nih.gov/pubmed/27095570
http://dx.doi.org/10.18632/oncotarget.8731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053622/
https://www.ncbi.nlm.nih.gov/pubmed/27095570
http://dx.doi.org/10.18632/oncotarget.8731

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