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Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression

Emerging studies on tumor cell-derived extracellular vesicles (EVs) have shown the biological significance in tumor development and microenvironment through reprogramming immune cells around cancer cells. In this study, we used colorectal cancer cells as EVs donor, and T cells as recipients to exami...

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Detalles Bibliográficos
Autores principales: Yamada, Nami, Kuranaga, Yuki, Kumazaki, Minami, Shinohara, Haruka, Taniguchi, Kohei, Akao, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053630/
https://www.ncbi.nlm.nih.gov/pubmed/27081032
http://dx.doi.org/10.18632/oncotarget.7041