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Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression
Emerging studies on tumor cell-derived extracellular vesicles (EVs) have shown the biological significance in tumor development and microenvironment through reprogramming immune cells around cancer cells. In this study, we used colorectal cancer cells as EVs donor, and T cells as recipients to exami...
Autores principales: | Yamada, Nami, Kuranaga, Yuki, Kumazaki, Minami, Shinohara, Haruka, Taniguchi, Kohei, Akao, Yukihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053630/ https://www.ncbi.nlm.nih.gov/pubmed/27081032 http://dx.doi.org/10.18632/oncotarget.7041 |
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