Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer

The signaling adaptor protein Crk has been shown to play an important role in various human cancers. However, its regulatory machinery is not clear. Here, we demonstrated that Crk induced EMT in A549 human lung adenocarcinoma cells through differential regulation of Rac1/Snail and RhoA/Slug, leading...

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Detalles Bibliográficos
Autores principales: Elmansuri, Aiman Z., Tanino, Mishie A., Mahabir, Roshan, Wang, Lei, Kimura, Taichi, Nishihara, Hiroshi, Kinoshita, Ichiro, Dosaka-Akita, Hirotoshi, Tsuda, Masumi, Tanaka, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053635/
https://www.ncbi.nlm.nih.gov/pubmed/27027347
http://dx.doi.org/10.18632/oncotarget.8314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053635/
https://www.ncbi.nlm.nih.gov/pubmed/27027347
http://dx.doi.org/10.18632/oncotarget.8314

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