Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

We recently introduced CDK5 as target in HCC, regulating DNA damage response. Based on this and on our previous knowledge about vascular effects of CDK5, we investigated the role of CDK5 in angiogenesis in HCC, one of the most vascularized tumors. We put a special focus on the transcription factor H...

Descripción completa

Detalles Bibliográficos
Autores principales: Herzog, Julia, Ehrlich, Sandra M., Pfitzer, Lisa, Liebl, Johanna, Fröhlich, Thomas, Arnold, Georg J., Mikulits, Wolfgang, Haider, Christine, Vollmar, Angelika M., Zahler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053636/
https://www.ncbi.nlm.nih.gov/pubmed/27027353
http://dx.doi.org/10.18632/oncotarget.8342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053636/
https://www.ncbi.nlm.nih.gov/pubmed/27027353
http://dx.doi.org/10.18632/oncotarget.8342

Ejemplares similares