The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma

Metabolic alterations underlying clear cell renal cell carcinoma (ccRCC) progression include aerobic glycolysis, increased pentose phosphate pathway activity and reduced oxidative phosphorylation. Phosphofructokinase (PFK), a key enzyme of the glycolytic pathway, has L, M, and P isoforms with differ...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jun, Zhang, Ping, Zhong, Jie, Tan, Mingyue, Ge, Jifu, Tao, Le, Li, Yakui, Zhu, Yemin, Wu, Lifang, Qiu, Jianxin, Tong, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053638/
https://www.ncbi.nlm.nih.gov/pubmed/27049827
http://dx.doi.org/10.18632/oncotarget.8382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053638/
https://www.ncbi.nlm.nih.gov/pubmed/27049827
http://dx.doi.org/10.18632/oncotarget.8382

Ejemplares similares