Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells

Brahma related gene product 1 (BRG1) is an ATPase that drives the catalytic activity of a subset of the mammalian SWI/SNF chromatin remodeling enzymes. BRG1 is overexpressed in most human breast cancer tumors without evidence of mutation and is required for breast cancer cell proliferation. We demon...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Sharma, Soni, Cui, Hang, LeBlanc, Scott E., Zhang, Hong, Muthuswami, Rohini, Nickerson, Jeffrey A., Imbalzano, Anthony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053639/
https://www.ncbi.nlm.nih.gov/pubmed/27029062
http://dx.doi.org/10.18632/oncotarget.8384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053639/
https://www.ncbi.nlm.nih.gov/pubmed/27029062
http://dx.doi.org/10.18632/oncotarget.8384

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