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Comparative genomic analysis of primary tumors and metastases in breast cancer

Personalized medicine uses genomic information for selecting therapy in patients with metastatic cancer. An issue is the optimal tissue source (primary tumor or metastasis) for testing. We compared the DNA copy number and mutational profiles of primary breast cancers and paired metastases from 23 pa...

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Detalles Bibliográficos
Autores principales: Bertucci, François, Finetti, Pascal, Guille, Arnaud, Adélaïde, José, Garnier, Séverine, Carbuccia, Nadine, Monneur, Audrey, Charafe-Jauffret, Emmanuelle, Goncalves, Anthony, Viens, Patrice, Birnbaum, Daniel, Chaffanet, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053643/
https://www.ncbi.nlm.nih.gov/pubmed/27028851
http://dx.doi.org/10.18632/oncotarget.8349