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LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway

Basal cell carcinomas (BCC) of the skin are the most common of human cancers. The noncanonical NF-κB pathway is dependent on IKKα. However, the role of IKKα in BCC has not been elucidated. We show here that IKKα is expressed in the nucleus in BCC and non-malignant diseases. Nuclear IKKα could direct...

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Detalles Bibliográficos
Autores principales: Jia, Jiantao, Shi, Ying, Yan, Bin, Xiao, Deshen, Lai, Weiwei, Pan, Yu, Jiang, Yiqun, Chen, Ling, Mao, Chao, Zhou, Jian, Xi, Sichuan, Cao, Ya, Liu, Shuang, Tao, Yongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053649/
https://www.ncbi.nlm.nih.gov/pubmed/27049829
http://dx.doi.org/10.18632/oncotarget.8465