Cargando…
LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway
Basal cell carcinomas (BCC) of the skin are the most common of human cancers. The noncanonical NF-κB pathway is dependent on IKKα. However, the role of IKKα in BCC has not been elucidated. We show here that IKKα is expressed in the nucleus in BCC and non-malignant diseases. Nuclear IKKα could direct...
Autores principales: | Jia, Jiantao, Shi, Ying, Yan, Bin, Xiao, Deshen, Lai, Weiwei, Pan, Yu, Jiang, Yiqun, Chen, Ling, Mao, Chao, Zhou, Jian, Xi, Sichuan, Cao, Ya, Liu, Shuang, Tao, Yongguang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053649/ https://www.ncbi.nlm.nih.gov/pubmed/27049829 http://dx.doi.org/10.18632/oncotarget.8465 |
Ejemplares similares
-
Opposed expression of IKKα: loss in keratinizing carcinomas and gain in non-keratinizing carcinomas
por: Xiao, Desheng, et al.
Publicado: (2015) -
Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radioresistance
por: Yan, Bin, et al.
Publicado: (2018) -
Decrease in Lymphoid Specific Helicase and 5-hydroxymethylcytosine Is Associated with Metastasis and Genome Instability
por: Jia, Jiantao, et al.
Publicado: (2017) -
New mouse genetic model of breast cancer from IKKα defects in dendritic cells revealed by single-cell RNA sequencing
por: Lai, Weiwei, et al.
Publicado: (2023) -
Baicalin hydrate inhibits cancer progression in nasopharyngeal carcinoma by affecting genome instability and splicing
por: Lai, Weiwei, et al.
Publicado: (2017)