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Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4α on hepatocellular carcinoma

Previous studies provided substantial evidence of a striking suppressive effect of hepatocyte nuclear factor 4α (HNF4α) on hepatocellular carcinoma (HCC). Apoptosis signal-regulating kinase 1 (ASK1) is involved in death receptor-mediated apoptosis and may acts as a tumor suppressor in hepatocarcinog...

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Detalles Bibliográficos
Autores principales: Jiang, Cai-Feng, Wen, Liang-Zhi, Yin, Chuan, Xu, Wen-Ping, Shi, Bin, Zhang, Xin, Xie, Wei-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053659/
https://www.ncbi.nlm.nih.gov/pubmed/27050273
http://dx.doi.org/10.18632/oncotarget.8478