Cargando…

Inhibition of skeletal growth of human prostate cancer by the combination of docetaxel and BKM1644: an aminobisphosphonate derivative

Bone metastasis is a major cause of prostate cancer (PCa) morbidity and mortality. Despite some success in transiently controlling clinical symptoms with docetaxel-based therapy, PCa patients become docetaxel-resistant and inevitably progress with no cure. We synthesized an acyl-tyrosine bisphosphon...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shumin, Gera, Lajos, Mamouni, Kenza, Li, Xin, Chen, Zhengjia, Kucuk, Omer, Wu, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053666/
https://www.ncbi.nlm.nih.gov/pubmed/27050371
http://dx.doi.org/10.18632/oncotarget.8481