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Pyrosequencing quantified methylation level of BRCA1 promoter as prognostic factor for survival in breast cancer patient
BRCA1 promoter methylation is an essential epigenetic transcriptional silencing mechanism, related to breast cancer (BC) occurrence and progression. We quantified the methylation level of BRCA1 promoter and evaluated its significance as prognostic and predictive factor. BRCA1 promoter methylation le...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053667/ https://www.ncbi.nlm.nih.gov/pubmed/27027444 http://dx.doi.org/10.18632/oncotarget.8355 |