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Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice

Cilia are present in most vertebrate tissues with a wide variety of functions, and abnormalities of cilia are linked to numerous human disorders. However, the molecular events underlying ciliary homeostasis are poorly understood. In this study, we generated double knockout (DKO) mice for the deubiqu...

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Detalles Bibliográficos
Autores principales: Ran, Jie, Yu, Fan, Qin, Juan, Zhang, Yijun, Yang, Yunfan, Li, Dengwen, Zhou, Jun, Liu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053669/
https://www.ncbi.nlm.nih.gov/pubmed/27028867
http://dx.doi.org/10.18632/oncotarget.8374