RSK-mediated down-regulation of PDCD4 is required for proliferation, survival, and migration in a model of triple-negative breast cancer

The p90 ribosomal S6 kinase (RSK) is a family of MAPK-activated serine/threonine kinases (RSK1-4) whose expression and/or activity are deregulated in several cancers, including breast cancer. Up-regulation of RSKs promotes cellular processes that drive tumorigenesis in Triple Negative Breast Cancer...

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Detalles Bibliográficos
Autores principales: Cuesta, Rafael, Holz, Marina K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053672/
https://www.ncbi.nlm.nih.gov/pubmed/27028868
http://dx.doi.org/10.18632/oncotarget.8375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053672/
https://www.ncbi.nlm.nih.gov/pubmed/27028868
http://dx.doi.org/10.18632/oncotarget.8375

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