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Hepatitis B virus X protein up-regulates C4b-binding protein α through activating transcription factor Sp1 in protection of hepatoma cells from complement attack

Hepatitis B virus X protein (HBx) plays crucial roles in the development of hepatocellular carcinoma (HCC). We previously showed that HBx protected hepatoma cells from complement attack by activation of CD59. Moreover, in this study we found that HBx protected hepatoma cells from complement attack b...

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Detalles Bibliográficos
Autores principales: Feng, Guoxing, Li, Jiong, Zheng, Minying, Yang, Zhe, Liu, Yunxia, Zhang, Shuqin, Ye, Lihong, Zhang, Weiying, Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053706/
https://www.ncbi.nlm.nih.gov/pubmed/27050367
http://dx.doi.org/10.18632/oncotarget.8472