Distinct epigenetic signatures elucidate enhancer-gene relationships that delineate CIMP and non-CIMP colorectal cancers

Epigenetic changes, like DNA methylation, affect gene expression and in colorectal cancer (CRC), a distinct phenotype called the CpG island methylator phenotype (“CIMP”) has significantly higher levels of DNA methylation at so-called “Type C loci” within the genome. We postulate that enhancer-gene p...

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Detalles Bibliográficos
Autores principales: Chong, Allen, Teo, Jing Xian, Ban, Kenneth H.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053707/
https://www.ncbi.nlm.nih.gov/pubmed/27049830
http://dx.doi.org/10.18632/oncotarget.8473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053707/
https://www.ncbi.nlm.nih.gov/pubmed/27049830
http://dx.doi.org/10.18632/oncotarget.8473

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