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miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma

The levels of expression of O(6)-methylguanine-DNA methyltransferase (MGMT) are relevant in predicting the response to the alkylating chemotherapy in patients affected by glioblastoma. MGMT promoter methylation and the published MGMT regulating microRNAs (miRNAs) do not completely explain the expres...

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Detalles Bibliográficos
Autores principales: Khalil, Susanna, Fabbri, Enrica, Santangelo, Alessandra, Bezzerri, Valentino, Cantù, Cinzia, Gennaro, Gianfranco Di, Finotti, Alessia, Ghimenton, Claudio, Eccher, Albino, Dechecchi, Maria, Scarpa, Aldo, Hirshman, Brian, Chen, Clark, Ferracin, Manuela, Negrini, Massimo, Gambari, Roberto, Cabrini, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053720/
https://www.ncbi.nlm.nih.gov/pubmed/27057640
http://dx.doi.org/10.18632/oncotarget.8618