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Gene therapy for colorectal cancer using adenovirus-mediated full-length antibody, cetuximab

Cetuximab is a chimeric monoclonal antibody, approved to treat patients with metastatic colorectal cancer (mCRC), head and neck squamous cell carcinoma (HNSCC), non-small-cell lung cancer (NSCLC) for years. It functions by blocking the epidermal growth factor receptor (EGFR) from receiving signals o...

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Detalles Bibliográficos
Autores principales: Xing, Man, Wang, Xiang, Chi, Yudan, Zhou, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053725/
https://www.ncbi.nlm.nih.gov/pubmed/27058423
http://dx.doi.org/10.18632/oncotarget.8596