Yin Yang-1 increases apoptosis through Bax activation in pancreatic cancer cells

The transcriptional regulator Yin Yang-1 (YY1) is a tumor suppressor known to be overexpressed in pancreatic cancer. We found that overexpression of YY1 promoted apoptosis and increased the expression and mitochondrial localization of the pro-apoptotic Bax protein in pancreatic cancer cell lines. Lu...

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Detalles Bibliográficos
Autores principales: Zhang, Jing-Jing, Zhu, Yi, Yang, Chuang, Liu, Xian, Peng, Yun-Peng, Jiang, Kui-Rong, Miao, Yi, Xu, Ze-Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053741/
https://www.ncbi.nlm.nih.gov/pubmed/27074573
http://dx.doi.org/10.18632/oncotarget.8654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053741/
https://www.ncbi.nlm.nih.gov/pubmed/27074573
http://dx.doi.org/10.18632/oncotarget.8654

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