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A loss-of-function genetic screening identifies novel mediators of thyroid cancer cell viability

RET, BRAF and other protein kinases have been identified as major molecular players in thyroid cancer. To identify novel kinases required for the viability of thyroid carcinoma cells, we performed a RNA interference screening in the RET/PTC1(CCDC6-RET)-positive papillary thyroid cancer cell line TPC...

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Detalles Bibliográficos
Autores principales: Cantisani, Maria Carmela, Parascandolo, Alessia, Perälä, Merja, Allocca, Chiara, Fey, Vidal, Sahlberg, Niko, Merolla, Francesco, Basolo, Fulvio, Laukkanen, Mikko O., Kallioniemi, Olli Pekka, Santoro, Massimo, Castellone, Maria Domenica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053742/
https://www.ncbi.nlm.nih.gov/pubmed/27058903
http://dx.doi.org/10.18632/oncotarget.8577