The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury

Much of the global cancer burden is associated with longstanding inflammation accompanied by release of DNA-damaging reactive oxygen and nitrogen species. Here, we report that the Mbd4 DNA glycosylase is protective in the azoxymethane/dextran sodium sulfate (AOM/DSS) mouse model of inflammation-driv...

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Detalles Bibliográficos
Autores principales: Yu, Amy Marie, Calvo, Jennifer A., Muthupalani, Suresh, Samson, Leona D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053750/
https://www.ncbi.nlm.nih.gov/pubmed/27086921
http://dx.doi.org/10.18632/oncotarget.8721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053750/
https://www.ncbi.nlm.nih.gov/pubmed/27086921
http://dx.doi.org/10.18632/oncotarget.8721

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