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Tumour-specific triple-regulated oncolytic herpes virus to target glioma

Oncolytic herpes simplex virus type 1 (oHSV-1) therapy is an emerging treatment modality that selectively destroys cancer. Here we report use of a glioma specific HSV-1 amplicon virus (SU4-124 HSV-1) to selectively target tumour cells. To achieve transcriptional regulation of the SU4-124 HSV-1 virus...

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Detalles Bibliográficos
Autores principales: Delwar, Zahid M., Liu, Guoyu, Kuo, Yvonne, Lee, Cleo, Bu, Luke, Rennie, Paul S., Jia, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053753/
https://www.ncbi.nlm.nih.gov/pubmed/27070093
http://dx.doi.org/10.18632/oncotarget.8637