A reciprocal regulatory circuit between CD44 and FGFR2 via c-myc controls gastric cancer cell growth

Despite their suggested importance, the mechanistic roles of FGFR2 and gastric cancer stem cell (GCSC) marker CD44 remain unclear. We investigated cross talk between CD44 and FGFR2. FGFR2 and CD44 positively regulate each other's expression. While FGFR2 suppresses c-Myc transcription, CD44 acti...

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Detalles Bibliográficos
Autores principales: Park, Jihyun, Kim, Sun Young, Kim, Ha-Jung, Kim, Kyoung-Mee, Choi, Eun Young, Kang, Myung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053754/
https://www.ncbi.nlm.nih.gov/pubmed/27107424
http://dx.doi.org/10.18632/oncotarget.8764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053754/
https://www.ncbi.nlm.nih.gov/pubmed/27107424
http://dx.doi.org/10.18632/oncotarget.8764

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