Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia

Epigenetic or transcriptional silencing of important tumor suppressors has been described to contribute to cell survival and tumorigenesis in chronic lymphocytic leukemia (CLL). Using gene expression microarray analysis, we found that thousands of genes are repressed more than 2-fold in CLL compared...

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Detalles Bibliográficos
Autores principales: Chen, Timothy L., Gupta, Nikhil, Lehman, Amy, Ruppert, Amy S., Yu, Lianbo, Oakes, Christopher C., Claus, Rainer, Plass, Christoph, Maddocks, Kami J., Andritsos, Leslie, Jones, Jeffery A., Lucas, David M., Johnson, Amy J., Byrd, John C., Hertlein, Erin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053755/
https://www.ncbi.nlm.nih.gov/pubmed/27107422
http://dx.doi.org/10.18632/oncotarget.8760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053755/
https://www.ncbi.nlm.nih.gov/pubmed/27107422
http://dx.doi.org/10.18632/oncotarget.8760

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