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Serotonin reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local antiresorptive effect

The use of selective serotonin reuptake inhibitors (SSRIs) has been associated with an increased risk of bone fracture, raising concerns about their increasingly broader usage. This deleterious effect is poorly understood and thus strategies to avoid this side effect remain elusive. We show here tha...

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Detalles Bibliográficos
Autores principales: Ortuño, María José, Robinson, Samuel T., Subramanyam, Prakash, Paone, Riccardo, Huang, Yung-yu, Guo, X. Edward, Colecraft, Henry M., Mann, J. John, Ducy, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053870/
https://www.ncbi.nlm.nih.gov/pubmed/27595322
http://dx.doi.org/10.1038/nm.4166