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Sodium channel Nav1.7 expression is upregulated in the dorsal root ganglia in a rat model of paclitaxel-induced peripheral neuropathy

Paclitaxel-induced peripheral neuropathy is not completely known. Since the sodium channel Nav1.7 has been implicated in pain perception, and is upregulated in pain disorders, we investigated the effect of paclitaxel on Nav1.7 expression in rat dorsal root ganglion (DRG) neurons. Thirty Sprague-Dawl...

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Detalles Bibliográficos
Autores principales: Xiao, Yun, Xia, Zhongyuan, Wu, Yang, Zhao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053969/
https://www.ncbi.nlm.nih.gov/pubmed/27777872
http://dx.doi.org/10.1186/s40064-016-3351-6