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Regulation of U6 Promoter Activity by Transcriptional Interference in Viral Vector-Based RNAi
The direct negative impact of the transcriptional activity of one component on the second one in cis is referred to as transcriptional interference (TI). U6 is a type III RNA polymerase III promoter commonly used for driving small hairpin RNA (shRNA) expression in vector-based RNAi. In the design an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054135/ https://www.ncbi.nlm.nih.gov/pubmed/20970745 http://dx.doi.org/10.1016/S1672-0229(10)60019-8 |