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Regulation of U6 Promoter Activity by Transcriptional Interference in Viral Vector-Based RNAi

The direct negative impact of the transcriptional activity of one component on the second one in cis is referred to as transcriptional interference (TI). U6 is a type III RNA polymerase III promoter commonly used for driving small hairpin RNA (shRNA) expression in vector-based RNAi. In the design an...

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Detalles Bibliográficos
Autores principales: Nie, Linghu, Thakur, Meghna Das, Wang, Yumei, Su, Qin, Zhao, Yongliang, Feng, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054135/
https://www.ncbi.nlm.nih.gov/pubmed/20970745
http://dx.doi.org/10.1016/S1672-0229(10)60019-8