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Identification of Potential Leptospira Phosphoheptose Isomerase Inhibitors Through Virtual High-Throughput Screening

The life-threatening infections caused by Leptospira serovars demand the need for designing anti-leptospirosis drugs. The present study encompasses exploring inhibitors against phosphoheptose isomerase (GmhA) of Leptospira, which is vital for lipopolysaccharide (LPS) biosynthesis and is identified a...

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Detalles Bibliográficos
Autores principales: Umamaheswari, Amineni, Pradhan, Dibyabhaba, Hemanthkumar, Marisetty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054147/
https://www.ncbi.nlm.nih.gov/pubmed/21382593
http://dx.doi.org/10.1016/S1672-0229(10)60026-5