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Role of Positive Selection Pressure on the Evolution of H5N1 Hemagglutinin

The surface glycoprotein hemagglutinin (HA) helps the influenza A virus to evade the host immune system by antigenic variation and is a major driving force for viral evolution. In this study, the selection pressure on HA of H5N1 influenza A virus was analyzed using bioinformatics algorithms. Most of...

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Detalles Bibliográficos
Autores principales: Duvvuri, Venkata R.S.K., Duvvuri, Bhargavi, Cuff, Wilfred R., Wu, Gillian E., Wu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054228/
https://www.ncbi.nlm.nih.gov/pubmed/19591791
http://dx.doi.org/10.1016/S1672-0229(08)60032-7