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Quantitative Non-canonical Amino Acid Tagging (QuaNCAT) Proteomics Identifies Distinct Patterns of Protein Synthesis Rapidly Induced by Hypertrophic Agents in Cardiomyocytes, Revealing New Aspects of Metabolic Remodeling

Cardiomyocytes undergo growth and remodeling in response to specific pathological or physiological conditions. In the former, myocardial growth is a risk factor for cardiac failure and faster protein synthesis is a major factor driving cardiomyocyte growth. Our goal was to quantify the rapid effects...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Kenney, Justin W., Manousopoulou, Antigoni, Johnston, Harvey E., Kamei, Makoto, Woelk, Christopher H., Xie, Jianling, Schwarzer, Michael, Garbis, Spiros D., Proud, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054342/
https://www.ncbi.nlm.nih.gov/pubmed/27512079
http://dx.doi.org/10.1074/mcp.M115.054312