Pomegranate extract decreases oxidative stress and alleviates mitochondrial impairment by activating AMPK-Nrf2 in hypothalamic paraventricular nucleus of spontaneously hypertensive rats

High blood pressure, or “hypertension,” is associated with high levels of oxidative stress in the paraventricular nucleus of the hypothalamus. While pomegranate extract is a known antioxidant that is thought to have antihypertensive effects, the mechanism whereby pomegranate extract lowers blood pre...

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Detalles Bibliográficos
Autores principales: Sun, Wenyan, Yan, Chunhong, Frost, Bess, Wang, Xin, Hou, Chen, Zeng, Mengqi, Gao, Hongli, Kang, Yuming, Liu, Jiankang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054377/
https://www.ncbi.nlm.nih.gov/pubmed/27713551
http://dx.doi.org/10.1038/srep34246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054377/
https://www.ncbi.nlm.nih.gov/pubmed/27713551
http://dx.doi.org/10.1038/srep34246

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