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In vivo analysis of internal ribosome entry at the Hairless locus by genome engineering in Drosophila

Cell communication in metazoans requires the highly conserved Notch signaling pathway, which is subjected to strict regulation of both activation and silencing. In Drosophila melanogaster, silencing involves the assembly of a repressor complex by Hairless (H) on Notch target gene promoters. We previ...

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Detalles Bibliográficos
Autores principales: Smylla, Thomas K., Preiss, Anette, Maier, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054391/
https://www.ncbi.nlm.nih.gov/pubmed/27713501
http://dx.doi.org/10.1038/srep34881