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How Do Variable Substitution Rates Influence Ka and Ks Calculations?

The ratio of nonsynonymous substitution rate (Ka) to synonymous substitution rate (Ks) is widely used as an indicator of selective pressure at sequence level among different species, and diverse mutation models have been incorporated into several computing methods. We have previously developed a new...

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Detalles Bibliográficos
Autores principales: Wang, Dapeng, Zhang, Song, He, Fuhong, Zhu, Jiang, Hu, Songnian, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054415/
https://www.ncbi.nlm.nih.gov/pubmed/19944384
http://dx.doi.org/10.1016/S1672-0229(08)60040-6