Zika virus infection during the period of maximal brain growth causes microcephaly and corticospinal neuron apoptosis in wild type mice

Zika virus (ZIKV) infection in pregnant women has been established as a cause of microcephaly in newborns. Here we test the hypothesis that neurodevelopmental stages when the brain is undergoing rapid growth are particularly vulnerable to the effects of ZIKV infection. We injected ZIKV intracraniall...

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Detalles Bibliográficos
Autores principales: Huang, Wen-Chin, Abraham, Rachy, Shim, Byoung-Shik, Choe, Hyeryun, Page, Damon T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054421/
https://www.ncbi.nlm.nih.gov/pubmed/27713505
http://dx.doi.org/10.1038/srep34793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054421/
https://www.ncbi.nlm.nih.gov/pubmed/27713505
http://dx.doi.org/10.1038/srep34793

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