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Zika virus infection during the period of maximal brain growth causes microcephaly and corticospinal neuron apoptosis in wild type mice
Zika virus (ZIKV) infection in pregnant women has been established as a cause of microcephaly in newborns. Here we test the hypothesis that neurodevelopmental stages when the brain is undergoing rapid growth are particularly vulnerable to the effects of ZIKV infection. We injected ZIKV intracraniall...
Autores principales: | Huang, Wen-Chin, Abraham, Rachy, Shim, Byoung-Shik, Choe, Hyeryun, Page, Damon T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054421/ https://www.ncbi.nlm.nih.gov/pubmed/27713505 http://dx.doi.org/10.1038/srep34793 |
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