Glibenclamide impairs responses of neutrophils against Burkholderia pseudomallei by reduction of intracellular glutathione

The major risk factor for melioidosis, an infectious disease caused by B. pseudomallei, is diabetes mellitus. More than half of diabetic melioidosis patients in Thailand were prescribed glibenclamide. Recent evidence demonstrates that glibenclamide reduces pro-inflammatory cytokine production by pol...

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Detalles Bibliográficos
Autores principales: Kewcharoenwong, Chidchamai, Rinchai, Darawan, Nithichanon, Arnone, Bancroft, Gregory J., Ato, Manabu, Lertmemongkolchai, Ganjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054430/
https://www.ncbi.nlm.nih.gov/pubmed/27713554
http://dx.doi.org/10.1038/srep34794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054430/
https://www.ncbi.nlm.nih.gov/pubmed/27713554
http://dx.doi.org/10.1038/srep34794

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