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Allosteric regulation in NMDA receptors revealed by the genetically encoded photo-cross-linkers

Allostery is essential to neuronal receptor function, but its transient nature poses a challenge for characterization. The N-terminal domains (NTDs) distinct from ligand binding domains are a major locus for allosteric regulation of NMDA receptors (NMDARs), where different modulatory binding sites h...

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Detalles Bibliográficos
Autores principales: Tian, Meilin, Ye, Shixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054432/
https://www.ncbi.nlm.nih.gov/pubmed/27713495
http://dx.doi.org/10.1038/srep34751